MCQs in Endocrine Biochemistry

1. Hormones
    a. Act as coenzyme
    b. Act as enzyme
    c. Influence synthesis of enzymes
    d. Belong to β-complex group

2. Hormone that binds to intracellular receptor is
    a. Adrenocorticotropic hormone
    b. Thyroxine
    c. Follicle stimulating hormone
    d. Glucagon

3. Hormone that bind to cell surface receptor and require the second messenger camp is
    a. Antidiuretic hormone
    b. Cholecystokinin
    c. Calcitriol
    d. Gastrin

4. A hormone secreted from anterior pituitary is
    a. Growth hormone
    b. Vasopressin
    c. Oxytocin
    d. Epinephrine

5. A hormone secreted from posterior pituitary is
    a. Vasopressin
    b. Thyrotropic hormone
    c. Prolactin
    d. Adrenocorticotropic hormone

6. The number of amino acids in human growth hormone is
    a. 91
    b. 151
    c. 191
    d. 291

7. Growth hormone causes hyperglycemia. It is a result of
    a. Decreased peripheral utilization of glucose
    b. Decreased hepatic production via gluconeogenesis
    c. Increased glycolysis in muscle
    d. Decrersed lipolysis

8. Acromegaly results due to excessive release of
    a. Thyroxine
    b. Growth hormone
    c. Insulin
    d. Glucagon

9. Growth hormone is released by
    a. Somatostatin
    b. Growth hormone releasing hormone
    c. Prolactin release inhibiting hormone
    d. Luteinizing releasing hormone

10. The number of amino acids in prolactin is
    a. 134
    b. 146
    c. 172
    d. 199

11. Adrenocorticotropic hormone (ACTH) is a single polypeptide containing
    a. 25 amino acid
    b. 39 amino acid
    c. 49 amino acid
    d. 52 amino acid

12. Thyroproxidase requires hydrogen peroxide as oxidizing agent. The H2O2 is produced by
    a. FADH2 dependent enzyme
    b. NADH dependent enzyme
    c. NADP dependent enzyme
    d. NADPH dependent enzyme

13. Thyroid stimulating hormone is a dimer. The α -subunits of TSH, LH, FSH are identical. Thus the biological specificity must therefore be β subunit in which the number of amino acids is
    a. 78
    b. 112
    c. 130
    d. 199

14. Following is a normal overnight fast and a cup of black coffee, a diabetic woman feels slightly nauseous and decides to skip breakfast. However she does take her shot of insulin. This may result in
    a. Heightened glycogenolysis
    b. Hypoglycemia
    c. Increased lipolysis
    d. Glycosuria

15. When thyroxine binding globulin and thyroxine binding pre-albumin are saturated with thyroxine, the excess hormone is transported by
    a. Albumin
    b. Gamma globulins
    c. Transcortin
    d. None of these

16. Hormonal stimulation of the formation of the second messenger inositol 1,4,5 triphosphate (IP3 ) quickly leads to the release of which other intracellular messenger?
    a. cAMP
    b. Prostaglandin
    c. Calcinon
    d. Leukotriene

17. Glucagon activates the enzyme adenylcyclase which causes the increase of blood sugar level. Hence this hormone is called
    a. Hypoglycemic factor
    b. Hyper glycemic factor
    c. Antidiauritic factor
    d. Thyrotropin-releasing factor

Ans: 1. C 2. B 3. A 4. A 5. A 6. C 7. A 8. B 9. B 10. D 11. B 12. D 13. B 14. B 15. A 16. C 17. B